FORMULATION AND EVALUATION OF SLN BASED TOPICAL GEL OF KETOROLAC TROMETHAMINE
نویسندگان
چکیده
منابع مشابه
Formulation and in vitro Evaluation of Dapsone Topical Gel 5%
Abstract Introduction: Dapsone gel (5%) is found to be effective in treating acne. The study was to develop a topical formulation of dapsone in Iran. Objective: Determination of appropriate formulation for generic form of this drug in the treatment of acne. Materials and Methods: Samples of the base of gel were made in the range of 0.3%-5% by dissolving Carbomer 934P in distilled water, and ...
متن کاملLecithin - Stabilized Microemulsion - Based Organogels for Topical Application of Ketorolac Tromethamine. II. Invitro Release Study
Ketorolac tromethamine (KT) containing microemulsion-based gels (MBGs) have been formulated, based on the previous phase diagram studies, using a pharmaceutically acceptable surfactant (soybean lecithin; Epikuron 200) and oil (isopropyl myristate; IPM) and the effect of formulation variables on the release profile of the drug from MBGs through intact guinea pig skin and various artificial membr...
متن کاملLecithin - Stabilized Microemulsion - Based Organogels for Topical Application of Ketorolac Tromethamine. II. Invitro Release Study
Ketorolac tromethamine (KT) containing microemulsion-based gels (MBGs) have been formulated, based on the previous phase diagram studies, using a pharmaceutically acceptable surfactant (soybean lecithin; Epikuron 200) and oil (isopropyl myristate; IPM) and the effect of formulation variables on the release profile of the drug from MBGs through intact guinea pig skin and various artificial membr...
متن کاملFormulation and Evaluation of Mouth Dissolving Tablet of Ketorolac Tromethamine for Pain Management by Using Superdisintegrants
s: Mouth dissolving tablet is the fast growing and highly accepted drug delivery system. This study was aimed at development of Ketorolac Tromethamine mouth dissolving tablet, which can disintegrate or dissolve rapidly once placed in the oral cavity. Conventional Ketorolac tromethamine tablet require water to swallow it and have disadvantages like low disintegration rate, low solubility etc.Ket...
متن کامل[Eyelid contact allergic eczema caused by topical ketorolac tromethamine 0.5%].
CLINICAL CASE A 65-year-old man had been treated with eye-drops containing NSAIDs (Ketorolac). He developed conjunctival injection, edematous swelling of the eyelids and periorbital dermatitis due to a contact allergy. Allergy to NSAIDs is uncommon. DISCUSSION This is an unusual case because topical application of ketorolac is safe in the vast majority of ophthalmologic patients. However adve...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences and Medicine
سال: 2021
ISSN: 2519-9889
DOI: 10.47760/ijpsm.2021.v06i03.008